Polynucleotides
What are Polynucleotides
These injectables have the ability to rejuvenate and regenerate the skin, similar to skin boosters like Seventy Hyal and Profhilo, however they have bio-stimulating properties. Polynucleotides are filtered, ultra-processed and sterilised DNA fractions with the aim of rejuvenating the skin. They're predominantly derived from salmon DNA.
Polynucleotides are designed to stimulate fibroblasts, promoting tissue repair, enhancing cell turnover, increasing elasticity and stimulating collagen production. Additionally they have the ability to balance skin pigmentation and resulting in a more even and balanced skin tone without adding volume like traditional dermal fillers.
Results are firmer skin which is highly moisturised with wrinkles and fine lines reduced. It also reduces dark circles and puffy eyes.
What are Polynucleotides used for
Acne scarring
Skin conditions such as rosacea, melasma and hyperpigmentation
Atrophic scarring
Alopecia and androgenic hair loss
Deep lines and sunken wrinkles
Skin rehydration and rejuvenation
Loss of elasticity (elastosis)
Facial ageing such as sagging and the formation of fine lines
Lumpy scars
Minimal Downtime and Discomfort level
One of the least painful treatments, you can resume your daily activities immediately after the procedure.
How long to see results
This differs from patient to patient, however results are usually seen in about three to five weeks, with the target results expected from 3+ months after the course of treatment has been offered.
Results also depend on the degree of ageing and its ability to create quality tissue when stimulated by the polynucleotide. It is important to maintain a healthy nutritious diet and reduce alcohol consumption and smoking to help repair the skin holistically.
Average sessions required
2-3 sessions one month apart
followed by top ups every 6-9 months
Who is a candidate for Polynucleotides
These are best suited to treat more mature skin and for patients showing early signs of ageing - perfect for those age 30 years and above.
Who is NOT a candidate for Polynucleotides
Pregnant or breastfeeding
Under 18 years of age
If you have an uncontrolled autoimmune disease
Keloid scarring (raised scarring that have expanded beyond the boundaries of the original wound)
If you have a fish allergy
Aftercare advice with Polynucleotides
Protect your skin immediately after treatment. You may experience lumps where the product has been injected, this is normal and can take between 24-72 hours to dissipate. If you experience mild redness or swelling apply a cold compress, however take care not to exert too much pressure. Avoid touching or massaging the treated areas.
Carefully plan your activities and Skincare. Avoid strenuous exercise, exposure to high temperatures (hot baths, steam rooms and saunas) 24-48 hours post treatment. Protect your skin from direct sunlight and wear a broad spectrum sunscreen.
Maintain hydration and follow a healthy nutritious diet. Keeping yourself hydrated is crucial, drink plenty of water and eat a diet rich in vitamins and antioxidants to aid in the skin's healing and rejuvenation process.
Long term skin care and maintenance. Use appropriate skin care and retinal to help with skin cell turnover and enhance results for longer. Use a broad spectrum sunscreen daily of 30+ in the winter and 50+ in the summer. Maintain your results with top ups every 6 to 9 months.
Potential side-effects with Polynucleotides
Injection site reactions. Redness, swelling, bruising and tenderness at the injection site, usually mild and resolve within a few days after treatment.
Allergic reactions. Allergy to components within the polynucleotide formula can occur and it is important to let your practitioner know your allergies.
Infection risk. Really rare but can occur. Avoid makeup for at least 12 hours post treatment. Avoid touching the area post treatment.
Temporary discomfort. This varies from person to person. Any discomfort or itching at the site of injection usually subsides quickly.
Rare complications. Very rare and more serious complications like granuloma formation or vascular complications can occur. These are significantly reduced when treated by a professional.
Photos courtesy of VITARAN, the first 100% quality-controlled polynucleotide injectable.